![]() There are mods on the workshop that provide details on how certain items work together. Some synergies also depend on the order that the player picks up the items. For example, picking up My Reflection and Ipecac will give the player exploding tears that arc back towards the player. ![]() ![]() ![]() However, not all item synergies are beneficial. Understanding what item synergies do is vital to completing some of the game's more difficult bosses. For example, picking up Brimstone and Mom's Knife will grant the player a brimstone stream made entirely out of knives. Synergies refer to how certain items can combine their effects to create stronger ones.
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